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Scleroderma (Systemic Sclerosis)
(RH010)
Introduction


Scleroderma is a disease of the skin, joints and sometimes, internal organs. Its cause is not known. Scleroderma means hardening (fibrosis) of the skin, and due to malfunction of the vascular and immune systems, results in the overproduction of collagen (connective tissue in the body). Scleroderma can be localized to the skin or may become systemic with excess collagen building up in various organs such as the esophagus, kidneys, lungs, gastrointestinal tract, heart skin, and peripheral nervous system.
Fortunately, scleroderma is relatively rare affecting approximately 300,000 persons in the United States. The disorder most commonly occurs in women between the ages of 20 and 40, however men and children can be affected as well. The disease is not contagious and is not thought to be inherited. Early diagnosis is important in allowing initiation of treatments designed to prevent long-term complications. Medications are commonly used. Surgery may be required for some conditions. Research is investigating bone marrow transplants for persons with scleroderma.
Get the Facts... With your MediFocus Guide


The Medifocus Guide on Scleroderma provides answers to the following important questions and medical issues:
  • What are the most common symptoms of scleroderma?
  • Are there any recognized risk factors for developing scleroderma?
  • What kinds of medical tests are used to establish the diagnosis of scleroderma?
  • What is the current standard of care for the treatment of scleroderma?
  • What treatment options are available for the management of scleroderma?
  • Are there any promising new developments or potential breakthroughs in treatment?
  • Who are the most notable medical authorities who specialize in scleroderma?
  • Where are the leading hospitals and centers of research for scleroderma?
  • What are the most important questions to ask my doctor about scleroderma?
What Your Doctor Reads:


This MediFocus Guide contains an extensive listing of citations and abstracts of recent journal articles that have been published about this condition in trustworthy medical journals. This is the same type of information that is available to physicians and other health care professionals. A partial selection of journal articles that are abstracted in this MediFocus Guide includes:
  • Prazosin for Raynaud's phenomenon in progressive systemic sclerosis.
    Cochrane Database of Systematic Reviews [computer file]. 2000
  • Cyclofenil for Raynaud's phenomenon in progressive systemic sclerosis.
    Cochrane Database of Systematic Reviews [computer file]. 2000
  • Ketanserin for Raynaud's phenomenon in progressive systemic sclerosis.
    Cochrane Database of Systematic Reviews [computer file]. 2000
  • Iloprost and cisaprost for Raynaud's phenomenon in progressive systemic sclerosis.
    Cochrane Database of Systematic Reviews [computer file]. 2000
  • De novo systemic sclerosis after radiotherapy: a report of 3 cases.
    Journal of Rheumatology. 1999
  • Polyneuropathy as initial manifestation of systemic sclerosis (scleroderma).
    Scandinavian Journal of Rheumatology. 1999
  • Morphea and localized scleroderma in children.
    Seminars in Cutaneous Medicine & Surgery. 1999
  • The treatment of systemic sclerosis.
    Advances in Experimental Medicine & Biology. 1999
  • Early diagnosis of systemic sclerosis.
    Advances in Experimental Medicine & Biology. 1999
  • Raynaud's phenomenon and vascular disease in systemic sclerosis.
    Advances in Experimental Medicine & Biology. 1999
MediFocus Guides... When You Need Trustworthy Medical Information

MediFocus.com understands that consumers who are facing serious medical issues need access to credible, up-to-date medical information to help them make informed health-care decisions. That's why we've developed the MediFocus Guides...the most advanced and trustworthy patient research guides for over 200 chronic and life-threatening conditions. Each MediFocus Guide includes a detailed overview of the condition including information about diagnosis, treatment options, cutting-edge research, and new developments; excerpts of important journal articles from the current medical literature focusing on standard treatments and treatment options; a directory of leading authors and medical institutions who specialize in the treatment of the condition; and a listing of organizations and support groups where you can obtain additional information about the illness.
MediFocus Guides are the perfect solution for consumers who wish to gain an in-depth understanding of their medical issue and avail themselves of the same type of professional level medical information that is used by physicians and other health-care professionals to help then in the clinical decision making process.
Medifocus: Your Personal Guide to Trustworthy Medical Information Get more data on this topic.
© Copyright 2000-2001 Medifocus.com, Inc. All rights reserved.

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