Psoriasis is a chronic skin disease marked by periodic flare-ups of sharply
defined red patches covered by a silvery, flaky surface. In psoriasis, the
epidermal cell cycle is accelerated. Cell division in the basal layer occurs
every 1.5 days and the migration of keratinocytes to the stratum corneum occurs
within just four days or so. Since the cells move to the surface so rapidly,
they do not differentiate and mature properly. The stratum corneum is not fully
keratinized, and epidermal cells build up abnormally and become scaly. The
epidermis in psoriatic lesions is three to five times thicker than
Psoriasis is a single disease with several forms of expression
and a range of severity. The form that psoriasis takes in an individual person
likely depends on genetic influences, environmental factors (e.g., traumatic and
climate), associated diseases (especially infections), medications, and the
status of the immune system.
The exact cause of psoriasis is unknown, but
it is thought that the primary process lies in the immune system with
significan't input from environmental factors. This is a focus of research for
The primary goals of care are control of the lesions,
minimization of side effects from treatment, and improvement in quality of life.
Current treatment utilizes a variety of topical medications as well as
ultraviolet light therapy.
Get the Facts... With your MediFocus
The Medifocus Guide on Psoriasis provides answers to the following important
questions and medical issues:
- What are the most common symptoms of psoriasis?
- Are there any recognized risk factors for developing psoriasis?
- What kinds of medical tests are used to establish the diagnosis of
- What is the current standard of care for the treatment of psoriasis?
- What treatment options are available for the management of psoriasis?
- Are there any promising new developments or potential breakthroughs in
- Who are the most notable medical authorities who specialize in
- Where are the leading hospitals and centers of research for psoriasis?
- What are the most important questions to ask my doctor about
What Your Doctor Reads:
This MediFocus Guide contains an extensive listing of citations and
abstracts of recent journal articles that have been published about this
condition in trustworthy medical journals. This is the same type of information
that is available to physicians and other health care professionals. A partial
selection of journal articles that are abstracted in this MediFocus Guide
- Better patient compliance in psoriasis.
- HIV-associated psoriasis.
AIDS Patient Care & STDS. 2000
Primary Care; Clinics in Office Practice. 2000
- Interventions for guttate psoriasis.
Cochrane Database of Systematic
Reviews [computer file]. 2000
- Treatment of psoriasis at the Dead Sea: why, how and when?.
Medical Association Journal: IMAJ. 2000
- Therapeutic strategies for psoriasis.
Journal of Clinical Pharmacy
& Therapeutics. 2000
- Pathophysiology and treatment of psoriasis.
American Journal of
Health-System Pharmacy. 2000
- Update on psoriasis therapy: a perspective from the USA.
Journal of Medicine. 2000
- Psoriasis, lichen planus, and disorders of keratinization: unapproved
treatments or indications.
Clinics in Dermatology. 2000
- Alcohol, smoking and psoriasis.
Clinical & Experimental
MediFocus Guides... When You Need
Trustworthy Medical Information
MediFocus.com understands that consumers who are facing serious
medical issues need access to credible, up-to-date medical information to help
them make informed health-care decisions. That's why we've developed the
MediFocus Guides...the most advanced and trustworthy patient research
guides for over 200 chronic and life-threatening conditions. Each MediFocus
Guide includes a detailed overview of the condition including information
about diagnosis, treatment options, cutting-edge research, and new developments;
excerpts of important journal articles from the current medical literature
focusing on standard treatments and treatment options; a directory of leading
authors and medical institutions who specialize in the treatment of the
condition; and a listing of organizations and support groups where you can
obtain additional information about the illness.
are the perfect solution for consumers who wish to gain an in-depth
understanding of their medical issue and avail themselves of the same type of
professional level medical information that is used by physicians and other
health-care professionals to help then in the clinical decision making process. Medifocus:
Your Personal Guide to Trustworthy Medical Information Get
more data on this topic.
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